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PROTONIX® (pantoprazole sodium) Contraindications

4 CONTRAINDICATIONS

  • PROTONIX is contraindicated in patients with known hypersensitivity to any component of the formulation or any substituted benzimidazole. Hypersensitivity reactions may include anaphylaxis, anaphylactic shock, angioedema, bronchospasm, acute interstitial nephritis, and urticaria [see Adverse Reactions (6)].
  • Proton pump inhibitors (PPIs), including PROTONIX, are contraindicated with rilpivirine-containing products [see Drug Interactions (7)].
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